Margreet Kloppenburg Selected Research

Osteoarthritis

4/2024	Comparative effectiveness of different placebos and comparator groups for hand osteoarthritis exploring the impact of contextual factors: A systematic review and meta-analysis of randomised trials.
11/2023	Synovial inflammation in osteoarthritis. A treatable target?
9/2023	Debate: Intra-articular steroid injections for osteoarthritis - harmful or helpful?☆,☆☆.
5/2023	Colchicine twice a day for hand osteoarthritis (COLOR): a double-blind, randomised, placebo-controlled trial.
1/2023	Serum biomarkers in prednisolone-treated hand osteoarthritis patients.
1/2023	Surgical denervation as a treatment strategy for pain in hand osteoarthritis: a systematic literature review.
1/2022	Neuropathic-like pain symptoms in inflammatory hand osteoarthritis lower quality of life and may not decrease under prednisolone treatment.
1/2022	Osteoarthritis endotype discovery via clustering of biochemical marker data.
12/2021	The lipid profile for the prediction of prednisolone treatment response in patients with inflammatory hand osteoarthritis: The HOPE study.
11/2021	Cripto favors chondrocyte hypertrophy via TGF-β SMAD1/5 signaling during development of osteoarthritis.

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Margreet Kloppenburg Research Topics

Disease

58	Osteoarthritis 04/2024 - 05/2005
31	Pain (Aches) 04/2024 - 07/2010
14	Inflammation (Inflammations) 01/2023 - 07/2010
9	Rheumatoid Arthritis 01/2023 - 04/2004
7	Synovitis 01/2023 - 07/2010
7	Knee Osteoarthritis 11/2022 - 08/2011
4	Disease Progression 12/2023 - 01/2013
4	Osteophyte 01/2019 - 10/2011
3	Arthritis (Polyarthritis) 11/2019 - 10/2007
3	Obesity 01/2018 - 08/2013
2	Rheumatic Diseases (Rheumatism) 01/2023 - 08/2014
2	Hip Osteoarthritis (Coxarthrosis) 01/2018 - 12/2011
2	Necrosis 01/2018 - 06/2012
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2023
1	Vasculitis (Vasculitides) 12/2023
1	Communicable Diseases (Infectious Diseases) 12/2023
1	Axial Spondyloarthritis 12/2023
1	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2023
1	Migraine Disorders (Migraine) 05/2023
1	Cholecystitis 05/2023
1	Gout 01/2023
1	Musculoskeletal Diseases (Musculoskeletal Disease) 01/2023
1	Neuralgia (Stump Neuralgia) 04/2022
1	Acromegaly 04/2022
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 11/2021
1	Hyperthyroidism 11/2021
1	Arthralgia (Joint Pain) 11/2021
1	Hypertrophy 11/2021
1	Fatigue 06/2021
1	Musculoskeletal Pain 01/2021
1	Knee Injuries (Knee Injury) 01/2021
1	Peritonitis 11/2020

Drug/Important Bio-Agent (IBA)

15	Biomarkers (Surrogate Marker)IBA 12/2023 - 09/2007
10	4-hexyloxyaniline (HOA)IBA 07/2021 - 07/2010
7	CytokinesIBA 11/2023 - 05/2005
6	LipidsIBA 12/2021 - 08/2013
5	Prednisolone (Predate)FDA LinkGeneric 01/2023 - 11/2019
4	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2023 - 12/2011
4	Interleukin-1 (Interleukin 1)IBA 11/2023 - 04/2010
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2011
4	LeptinIBA 02/2016 - 07/2011
4	AdiponectinIBA 05/2014 - 07/2011
3	C-Reactive ProteinIBA 01/2023 - 11/2018
3	AutoantibodiesIBA 01/2022 - 01/2019
3	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2021 - 04/2014
3	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 11/2020 - 01/2018
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2011 - 05/2005
3	Interleukin-10 (Interleukin 10)IBA 08/2010 - 05/2005
2	Analgesics (Analgesic Drugs)IBA 04/2022 - 12/2011
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2019 - 01/2014
2	InterleukinsIBA 01/2019 - 08/2010
2	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2018 - 01/2011
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2018 - 01/2018
2	GlucocorticoidsIBA 01/2018 - 01/2018
2	GadoliniumIBA 07/2015 - 04/2004
2	ResistinIBA 09/2011 - 07/2011
2	AdipokinesIBA 09/2011 - 07/2011
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 08/2010 - 04/2010
2	LipopolysaccharidesIBA 04/2010 - 05/2005
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 04/2010 - 05/2005
1	PlacebosIBA 04/2024
1	Interleukin-23 (Interleukin 23)IBA 12/2023
1	5- chloro- 3- tert- butyl- 2'- chloro- 4'- nitrosalicylanilide (S 13)IBA 12/2023
1	P-30 composite resin (P 30)IBA 12/2023
1	SteroidsIBA 09/2023
1	Colchicine FDA LinkGeneric 05/2023
1	Alanine Transaminase (SGPT)IBA 05/2023
1	RadonIBA 01/2023
1	VimentinIBA 01/2023
1	Uric Acid (Urate)IBA 01/2023
1	Collagen Type V (Type V Collagen)IBA 01/2023
1	Collagen Type III (Type III Collagen)IBA 01/2023
1	aggrecanaseIBA 01/2023
1	catch-relaxing peptide (Mytilus)IBA 01/2023
1	Collagen Type I (Type I Collagen)IBA 01/2023
1	Matrix Metalloproteinases (MMPs)IBA 01/2023
1	Prednisone (Sone)FDA LinkGeneric 01/2022
1	VLDL LipoproteinsIBA 11/2021
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 11/2021
1	Triglycerides (Triacylglycerol)IBA 11/2021
1	Lipoproteins (Lipoprotein)IBA 11/2021
1	Transforming Growth Factors (Transforming Growth Factor)IBA 11/2021
1	ORALIT (ORS)IBA 11/2021
1	Phosphotransferases (Kinase)IBA 11/2021
1	Activin Receptors (Activin Receptor)IBA 11/2021
1	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 06/2021
1	MicroRNAs (MicroRNA)IBA 01/2021
1	Vitamin K FDA Link 01/2021
1	Nerve Growth Factor (NGF)IBA 12/2020
1	Peptide Hydrolases (Proteases)FDA Link 12/2020
1	Leukotriene B4IBA 11/2020

Therapy/Procedure

11	Therapeutics 12/2023 - 03/2007
4	Injections 09/2023 - 12/2011
3	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2021 - 02/2012
2	Self-Help Devices (Assistive Technology) 04/2014 - 01/2011
2	Replacement Arthroplasty 09/2012 - 08/2011
1	Precision Medicine 12/2023
1	Denervation 01/2023
1	Oral Hygiene (Dental Hygiene) 11/2021